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Test Code PGSN Progesterone, Serum

Reporting Name

Progesterone, S

Useful For

Ascertaining whether ovulation occurred in a menstrual cycle

 

Assessment of infertility

 

Evaluation of abnormal uterine bleeding

 

Evaluation of placental health in high-risk pregnancy

 

Determining the effectiveness of progesterone injections when administered to women to help support early pregnancy

 

Workup of some patients with adrenal disorders

Method Name

Electrochemiluminescence Immunoassay (ECLIA)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).

Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged, and serum aliquoted into a plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 180 days
  Refrigerated  72 hours
  Ambient  8 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Reference Values

<4 weeks: Not established

4 weeks-<12 months: ≤0.66 ng/mL (Confidence Interval: 0.63-0.94 ng/mL)

12 months-9 years: ≤0.35 ng/mL

10-17 years: Concentrations increase through adolescence and puberty

≥ 18 years: <0.20 ng/mL

Reference intervals are central 90th percentile of healthy population

 

Females:

<4 days old: Not established

4 days-<12 months: ≤1.3 ng/mL (Confidence Interval: 0.88-2.3 ng/mL)

12 months-9 years: ≤0.35 ng/mL

10-17 years: Adult concentrations are attained by puberty

≥ 18 years:

Reference intervals are central 90th percentile of healthy population

-Follicular phase: ≤0.89 ng/mL

-Ovulation: ≤12 ng/mL

-Luteal phase: 1.8-24 ng/mL

-Post-menopausal: ≤0.20 ng/mL

Pregnancy

-1st trimester: 11-44 ng/mL

-2nd trimester: 25-83 ng/mL

-3rd trimester: 58-214 ng/mL

 

Pediatric reference intervals adopted from the CALIPER study. https://caliperproject.ca/caliper/database/

 

For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html.

Day(s) Performed

Monday through Sunday

CPT Code Information

84144

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PGSN Progesterone, S 83109-9

 

Result ID Test Result Name Result LOINC Value
PGSN Progesterone, S 83109-9

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

Same day/1 day