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HelpTest Code NSE Neuron-Specific Enolase, Serum
Reporting Name
Neuron Specific Enolase, SUseful For
A follow-up marker in patients with neuron-specific enolase-secreting tumors of any type
An auxiliary test in the diagnosis of small cell lung carcinoma
An auxiliary test in the diagnosis of carcinoids, islet cell tumors, and neuroblastomas
An auxiliary tool in the assessment of comatose patients
Method Name
Homogeneous Time-Resolved Fluorescence
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Specimens should not be transported by tube system prior to centrifugation.
2. Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Ambient | 5 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
| Hemolysis at any level | Reject |
Reference Values
≤15 ng/mL
Serum markers are not specific for malignancy, and values may vary by method.
Day(s) Performed
Monday through Saturday
CPT Code Information
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NSE | Neuron Specific Enolase, S | 15060-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| NSE | Neuron Specific Enolase, S | 15060-7 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
1 to 3 daysForms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.