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HelpTest Code MMAS Methylmalonic Acid, Quantitative, Serum
Reporting Name
Methylmalonic Acid, QN, SUseful For
Evaluating children with signs and symptoms of methylmalonic acidemia using serum specimens
Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume:1.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 48 days | |
| Ambient | 48 days | ||
| Frozen | 48 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
≤0.40 nmol/mL
Day(s) Performed
Monday through Friday
CPT Code Information
83921
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MMAS | Methylmalonic Acid, QN, S | 13964-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80289 | Methylmalonic Acid, QN, S | 13964-2 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
3 to 5 daysForms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-General Request (T239)
-Benign Hematology Test Request (T755)