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Test Code FB12 Vitamin B12 and Folate, Serum

Reporting Name

Vitamin B12 and Folate, S

Useful For

Investigation of macrocytic anemia

 

Workup of deficiencies seen in megaloblastic anemias

 

Investigation of suspected folate deficiency

Profile Information

Test ID Reporting Name Available Separately Always Performed
B12 Vitamin B12 Assay, S Yes Yes
FOL Folate, S Yes Yes

Testing Algorithm

For more information, see Vitamin B12 Deficiency Evaluation.

Method Name

B12: Immunoenzymatic Assay

FOL: Competitive Binding Receptor Assay

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparation:

1. Patient should be fasting for 8 hours.

2. Do not order on patients who have recently received methotrexate or other folic acid antagonists.

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  90 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Special Instructions

Reference Values

VITAMIN B12

180-914 ng/L

 

FOLATE

≥4.0 mcg/L

<4.0 mcg/L suggests folate deficiency

Day(s) Performed

Monday through Friday

CPT Code Information

82607-Vitamin B12

82746-Folate

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FB12 Vitamin B12 and Folate, S 96805-7

 

Result ID Test Result Name Result LOINC Value
B12 Vitamin B12 Assay, S 2132-9
FOL Folate, S 2284-8

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

1 to 3 days

Forms

If not ordering electronically, complete, print, and send a Benign Hematology Test Request Form (T755) with the specimen.